Autogen
Generative AI platform for creating autonomous agents and automating workflows.
A leading, free multi-agent framework that is great for prototypes - but now in maintenance mode, so plan for its successor on long-lived projects.
Microsoft Research's open-source framework for building multi-agent AI systems, where LLM agents converse, delegate and loop in humans to solve tasks.
It pioneered chat-centric, asynchronous multi-agent orchestration and remains one of the fastest paths from an API key to a working agent team, with AutoGen Studio for low-code prototyping. The big 2026 caveat: it is now in maintenance mode (bug fixes only), with Microsoft steering new work to the Microsoft Agent Framework - so build with a migration plan.
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Alternatives
Microsoft Agent Framework - the enterprise-ready successor with long-term support.
CrewAI - simpler, structured multi-agent teams with fast time-to-production.
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